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Zhu et al. were the first to provide evidence that TiO2 NPs (21 nm) can transfer from daphnia to zebrafish by dietary exposure. Hence, dietary intake could be a major route of exposure to NPs for high trophic level aquatic organisms. Ecological research should therefore focus, not only on the concentration of NPs in the environment, but also on its bioconcentration, bioaccumulation and biomagnification. In addition it has been shown that TiO2 NPs can increase accumulation of other environmental toxicants: enhanced accumulation of cadmium (Cd) and arsenic (As) was found in carp in the presence of TiO2 NPs. The strong adsorption capacity for Cd and As was explained by the large specific surface area and strong electrostatic attraction of TiO2 NPs that contribute to facilitated transport into different organs.

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One of the primary uses of titanium dioxide is as a pigment in cosmetics and personal care products. It provides a natural, white color to products such as foundations, powders, and lipsticks, making them look more appealing to users. Additionally, titanium dioxide has excellent UV protection properties, which help protect the skin from harmful sun rays. This makes it an essential ingredient in sunscreens and other skincare products.

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